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Very often,
you have heard people in situations like this one say that they
are pleased to introduce a particular speaker. Today, I am not only
pleased, I feel privileged and honoured because I have been asked
by our president, Dr. Lorraine Allan, to introduce to you the winner
of this year's BBCS Donald O. Hebb Award, and because this gives
me the chance to say a few words about the person who, for many
years, has been an academic inspiration: my mentor Dr. Brenda Milner.
Brenda
Milner was born in Manchester and grew up in England. When it came
time to go to university, unlike most of us, she applied only to
the University of Cambridge where she completed her Bachelor's degree
in Experimental Psychology. She then came to Canada to teach at
the University of Montreal. During this period, she also completed
a Master's degree in Experimental Psychology at Cambridge, and shortly
thereafter, a Ph.D. in Physiological Psychology at McGill University
under the supervision of Dr. Hebb, in whose honour we present this
award. How appropriate that she receives this prize!
She set
the tone of her career very early on by going against Hebb's advice
to study patients of Dr. Wilder Penfield at the Montreal Neurological
Institute. There, she decided to build her scientific career studying
brain-function relationships, first through behavioural studies
in patients who undergo focal removal of cerebral tissue for the
treatment of intractable epilepsy, and more recently, through brain
imaging studies using positron emission tomography (PET) and functional
magnetic resonance imaging (fMRI). Her work has clearly had a major
impact in several areas of research in neuroscience. For example,
her observations in the patient H.M. did not only enlighten the
scientific community with regard to the importance of the medial
structures of the temporal lobes in memory, but were also the first,
clear, demonstration of the existence of multiple memory systems
in the brain. However, her contributions to the field of memory
cannot, and must not, be limited to her work with H.M. In fact,
her pioneering and meticulous studies of the effects of lesions
to the temporal and frontal regions of the brain, has allowed us
to understand better the role of these cerebral structures in different
forms of memory processes, as well as in other cognitive functions.
The results of these investigations have since served as the knowledge
base necessary for carrying out neuropsychological evaluations of
a variety of patients with neurological disorders. Also, let us
not forget about her success in developing, in collaboration with
Dr. Rasmussen, the Sodium Amytal test (also called the Wada test),
which has made a major difference in the pre-surgical care of patients
and the decision making processes of neurosurgeons facing the difficult
task of having to remove brain tissue that might be critical for
language or memory functions.
Without
a doubt, Brenda is appropriately considered
as one of the most influential scientists
on the Canadian scene, not only in neuroscience, but in science
as a whole. For her outstanding contributions to our discipline,
she has received numerous honours and prizes. Let me just mention
a few that, I believe, she treasures. In 1980, she received her
first doctorate honoris causa from Queen's University (in Kingston,
Ontario). Since then, she has received 14 other honorary degrees:
one from Laval University in 1987, one from the University of
Montreal in 1988, one from McGill University in 1991, and a very
special one last year from her alma mater, Cambridge. In addition
to these distinctions, she has been awarded several prizes including
a Career Investigator award from the Medical Research Council
of Canada, which has supported her salary for 36 years. She has
also been given the Distinguished Scientific Contribution Award
of the American Psychological Association and the Izaak Walton
Killam Memorial prize (by The Canada Council). She has been named
Fellow of the Royal Society of London, Fellow of the Royal Society
of Canada, Officer of the Order of Canada, Officier de l'Ordre
national du Québec (by René Lévesque), Femme de l'année
en sciences au Québec, and Fellow Associate of the National
Academy of Science in United States.
Finally, in 1997, Canada recognized
the importance of her tremendous contributions to science, and
her role as a founder of neuropsychology, by electing her to the
Canadian Medical Hall of Fame.
Throughout
her career, Brenda has played a major
role in the politico-scientific arena,
by accumulating positions on numerous
editorial boards of prestigious journals and committees of several
international organizations. Most important to her, however,
is the guidance that she has been able to provide to students
and post-doctoral fellows that she calls fondly "The Troops." She
has inspired many scientists who have
forged distinguished careers of their
own: Doreen Kimura, Suzanne Corkin, Brian Kolb, Morris Moscovitch
and Michael Petrides to name a few.
Now, for
those of you who think that she might be considering retirement
after having accomplished so much already: this is obviously not
an option! She still has research projects funded by the Canadian
Institutes of Health Research and is supervising post-doctoral fellows.
In all senses of the word, Brenda is really an exceptional woman
who lives her life through science. Her commitment to excellence
is demonstrated by her rigorous approach to research and writing
(how many of you have heard of the Manchester Filter?). I would
say that her modus vivendi is to push the quality of work in science
to its utmost limits. And, she enjoys the good things in life like
a fine bottle of wine, an exquisite meal and a good laugh. In fact,
Brenda can recall even minute details about specific meals (like
when, where, with whom) that she has had over the years; a subject
that may be closely related to the topic of her talk today entitled: "Memory
and the right temporal lobe: From patients to imaging." Please
join me in welcoming this year's winner of the Donald O. Hebb Award:
the inimitable Dr. Brenda Milner.
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